Alzheimer’s disease as the cerebral cortex disorder
Objectives – to highlight the structure, function and localization of Alzheimer’s disease and to specify cognitive impairments related to it.
Material and methods. The anatomic data of human brain structure were used.
Results. The patterns of memory formation in the brain cortex are investigated. The brain cortex is presented as a type of syncytium consisting of elementary neural structures – cyclic neuronal circuits – memory elements. All cyclic neuronal circuits in a brain cortex are functionally interconnected. The connections between the neuronal circuits can be determined (imprinted) and stochastic (random). The intensity of stochastic communications defines the person's potential for creativity. The impairment of cyclic neuronal circuit connections results in either Alzheimer’s disease or in senile dementia of Alzheimer’s type.
Conclusion. In case the cortex is considered as the syncytium, the memory storage element, it can be the reason of the human creativity. It is shown that the failure of the information transfer in the cortex syncytium or neurons destruction in the neuronal network results in Alzheimer’s disease or in senile dementia of Alzheimer’s type.
Conflict of Interest: nothing to disclose.
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Volobuev AN, Romanchuk PI, Bulgakova SV. Alzheimer’s disease as the cerebral cortex disorder. Science & Innovations in Medicine.2019;4(2):16-20. DOI: 10.35693/2500-1388-2019-4-2-16-20
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