I.P. Pavlov Journal of Higher Nervous ActivityI.P. Pavlov Journal of Higher Nervous ActivityЖурнал высшей нервной деятельности им. И.П. Павлова0044-46773034-5316The Russian Academy of Sciences65201410.31857/S0044467723050106TRWMSZФИЗИОЛОГИЯ ВЫСШЕЙ НЕРВНОЙ (КОГНИТИВНОЙ) ДЕЯТЕЛЬНОСТИ ЧЕЛОВЕКАФИЗИОЛОГИЯ ВЫСШЕЙ НЕРВНОЙ (КОГНИТИВНОЙ) ДЕЯТЕЛЬНОСТИ ЧЕЛОВЕКАINCREASE OF INTRACRANIAL EEG ALPHA PEAK FREQUENCY AS A RESPONSE TO THE OWN-NAME STIMULUS DURING GENERAL ANESTHESIA IN ELEVEN PATIENTS WITH BRAIN TUMORSУвеличение пиковой частоты альфа-ритма ээг при предъявлении собственного имени во время глубокой анестезииPortnovaG. V.ПортноваГ. В.caviter@list.ruKantserovaA. O.КанцероваА. О.caviter@list.ruOkninaL. B.ОкнинаЛ. Б.caviter@list.ruPitskhelauriD. I.ПицхелауриД. И.caviter@list.ruPodlepichV. V.ПодлепичВ. В.caviter@list.ruVologdinaYa. O.ВологдинаЯ. О.caviter@list.ruMasherovE. L.МашеровЕ. Л.caviter@list.ruInstitute of Higher Nervous Activity and Neurophysiology RASФГБУН Институт Высшей Нервной Деятельности и Нейрофизиологии РАНBurdenko Institute of Neurosurgery, Ministry of Health of RussiaФГАУ “НМИЦ Нейрохирургии им. ак. Н.Н. Бурденко”0109202373562263602022025Copyright ©; 2023, Г.В. Портнова, А.О. Канцерова, Л.Б. Окнина, Д.И. Пицхелаури, В.В. Подлепич, Я.О. Вологдина, Е.Л. МашеровCopyright ©; 2023, Г.В. Портнова, А.О. Канцерова, Л.Б. Окнина, Д.И. Пицхелаури, В.В. Подлепич, Я.О. Вологдина, Е.Л. Машеров2023Г.В. Портнова, А.О. Канцерова, Л.Б. Окнина, Д.И. Пицхелаури, В.В. Подлепич, Я.О. Вологдина, Е.Л. МашеровГ.В. Портнова, А.О. Канцерова, Л.Б. Окнина, Д.И. Пицхелаури, В.В. Подлепич, Я.О. Вологдина, Е.Л. Машеровhttps://innoscience.ru/0044-4677/article/view/652014

The few existing studies demonstrated that hearing one’s name could have an arousal or alertness impact during unconsciousness. At the same time, the brain areas involved in this reactivity remained unknown. In this study, we attempted to register a response from two brain areas, the mesencephalon and cerebral cortex, in eleven patients who underwent posterior third ventricle or posterior fossa tumor removals under general anesthesia. We used 2 deep electrodes and 16 scalp electrodes and a registered electroencephalogram (EEG) for 2 states: the resting state, and stimulation state (which included sounds of one’s name, another name, and noise, presented in random order). Our results indicated that patients under general anesthesia could respond to their names (demonstrated by accelerated alpha-peak frequency), compared to other sounds and the resting state EEG, which was registered both on the cerebral and mesencephalon levels, indicating activated brain systems.

Восприятие эмоционально значимых звуков у пациентов с угнетением сознания остается актуальной темой. Данные литературы свидетельствуют о том, что собственное имя, подаваемое в виде звукового сигнала, является одним из стимулов, способных оказывать активирующее действие на субъектов, находящихся в бессознательном состоянии. В данной работе мы исследовали электрофизиологическую реакцию пациентов, находящихся под глубоким наркозом во время проведения нейрохирургической операции, с целью оценить влияние глубины наркоза на восприятие звуков, в том числе и собственного имени, и исследовать области мозга, вовлеченные в их анализ. Мы регистрировали ЭЭГ синхронно от 12 скальповых электродов и на уровне среднего мозга от двух глубинных электродов в состоянии покоя и при предъявлении звуковых стимулов (собственное имя, чужое имя и шум) у одиннадцати пациентов сразу после удаления опухоли задних отделов третьего желудочка или четвертого желудочка. Результаты показали, что пациенты, находящиеся под глубоким наркозом, могли реагировать на свое имя в виде увеличения пиковой частоты альфа-ритма, по сравнению с чужими именами, шумами, а также в сравнении с ЭЭГ в состоянии покоя, как на уровне скальповой ЭЭГ в височных областях, так и на уровне среднего мозга.

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