I.P. Pavlov Journal of Higher Nervous ActivityI.P. Pavlov Journal of Higher Nervous ActivityЖурнал высшей нервной деятельности им. И.П. Павлова0044-46773034-5316The Russian Academy of Sciences65206910.31857/S0044467724050019ОБЗОРЫ И ТЕОРЕТИЧЕСКИЕ СТАТЬИReview ArticleRepresentation of spatial information in the CA1 fieldПредставление пространственной информации в поле СА1MysinI. E.МысинИ. Е.
Russian Federation

Laboratory of the Systemic Organization of Neurons

Лаборатория cистемной организации нейронов

imysin@mail.ruVasilevA. O.ВасильевА. О.
Russian Federation

Laboratory of the Systemic Organization of Neurons

Лаборатория cистемной организации нейронов

imysin@mail.ruDubrovinS. V.ДубровинС. В.
Russian Federation
imysin@mail.ruSkorokhodS. N.СкороходС. Н.
Russian Federation
imysin@mail.ruInstitute of Theoretical and Experimental Biophysics oof the Russian Academy of SciencesИнститут теоретической и экспериментальной биофизики РАНUfa University of Science and TechnologyФГБОУ ВО «Уфимский университет науки и технологий»Peter the Great St. Petersburg Polytechnic University UniversityСанкт-Петербургский политехнический университет им. Петра Великого2611202474551753702022025Copyright ©; 2024, Russian Academy of SciencesCopyright ©; 2024, Российская академия наук2024Russian Academy of SciencesРоссийская академия наукhttps://innoscience.ru/0044-4677/article/view/652069

Information in the brain is encoded by large populations of neurons – neural ensembles. The place cells in the hippocampal CA1 field have become an experimental model for the study of neural ensembles of the brain due to the convenience of research. This review is devoted to the latest studies of place cells in the CA1 field. We consider the principles of encoding space by place cells, mechanisms for controlling the activity of place cells, anatomical and physiological features of place cells in different parts of the CA1 field. Key points: 1. There are rate and phase coding; 2. Dense local connections between pyramidal neurons can provide information processing; 3. Interneurons are involved in the formation of both the rate and phase code of place cells; 4. Pyramidal neurons are anatomically and functionally divided into deep and superficial; 5. Along the dorsoventral axis, the spatial and non-spatial component of information is generalized. The CA1 field has extensive capabilities for signal processing and can implement a computationally complex operation in the cognitive processes of the brain.

Информация в мозге кодируется большими популяциями нейронов – нейронными ансамблями. Клетки места в поле СА1 гиппокампа стали экспериментальной моделью изучения нейронных ансамблей мозга в силу удобства исследования. Этот обзор посвящен последним исследованиям клеток места в поле СА1. Мы рассматриваем принципы кодирования пространства клетками места, механизмы контроля активности клеток места, анатомические и физиологические особенности клеток места в разных частях поля СА1. Ключевые выводы: 1) Существует частотное и фазовое кодирование; 2) Плотные локальные связи между пирамидными нейронами могут обеспечивать обработку информации; 3) Интернейроны участвуют в формировании как частотного, так и фазового кода клеток места; 4) Пирамидные нейроны анатомически и функционально подразделяются на глубокие и поверхностные; 5) Вдоль дорсовентральной оси происходит обобщение пространственного и непространственного компонента информации. Поле СА1 имеет широкие возможности для обработки сигналов и может реализовать вычислительно сложную операцию в когнитивных процессах мозга.

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