SPERM QUALITY AND FEATURES OF THE ANTIOXIDANT DEFENSE SYSTEM IN MEN LIVING IN VARIOUS REGIONS OF SIBERIA
- Authors: Kolesnikova L.I1, Kurashova N.A1, Dolgikh M.I1, Natyaganova L.V1, Dashiyev B.G2
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Affiliations:
- Scientific Center for Family Health and Reproduction
- Republican Perinatal Center
- Issue: No 6 (2016)
- Pages: 107-109
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/286618
- ID: 286618
Cite item
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Abstract
Aim To investigate the quality of sperm, total antioxidant activity, concentrations of α-tocopherol and lipid peroxidation in men of reproductive age living in Ulan-Ude, Irkutsk, and Novosibirsk. Materials and methods The analysis of sperm quality included measuring the volume and pH of the ejaculate, sperm cell count, the proportion of motile sperm cells of A and B categories. Results Healthy men living in Irkutsk were found to have 34.4 and 23.6% higher sperm count (millions per ml) compared to men living in the city of Novosibirsk and Ulan-Ude, respectively. They also had a 44 and 38% statistically significantly greater concentration of alpha-tocopherol than men living in Ulan-Ude and Novosibirsk, respectively. Men from Ulan-Ude had 16 and 11% greater counts of active spermatozoa than men from Novosibirsk, respectively, and 34 and 13% higher levels of total antioxidant activity of ejaculate, respectively. Conclusion The findings on quality of the ejaculate and features of lipid peroxidation in men living in various Siberian cities show that the place of residence and ecological and geographical location affect functioning of the reproductive system and the heterogeneity of male infertility under anthropogenic pressure.
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About the authors
L. I Kolesnikova
Scientific Center for Family Health and Reproduction
Email: iphr@sbamsr.irk.ru
Irkutsk
N. A Kurashova
Scientific Center for Family Health and Reproduction
Email: nakurashova@yandex.ru
PhD (bio.sci.), Researcher at the Laboratory of Reproductive Pathophysiology Irkutsk
M. I Dolgikh
Scientific Center for Family Health and Reproduction
Email: iphr@sbamsr.irk.ru
Irkutsk
L. V Natyaganova
Scientific Center for Family Health and Reproduction
Email: iphr@sbamsr.irk.ru
Irkutsk
B. G Dashiyev
Republican Perinatal CenterUlan-Ude
References
- Колесникова Л.И., Колесников С.И., Курашова Н.А., Баирова Т.А. Причины и факторы риска мужской инфертильности. Вестник РАМН. 2015;5:579-584. doi: 10.15690/vramn.v70.i5.1445
- Brody S. Male factor infertility and oxidative stress: role of diet, lifestyle and nutritional supplements. Androl. Genit. Surg. 2014;3:33-41.
- Jensen T.K., Heitmann B.L., Blomberg Jensen M., Halldorsson T.I., Andersson A.M., Skakkebæk N.E., Joensen U.N., Lauritsen M.P., Christiansen P., Dalgård C., Lassen T.H., Jorgensen N. High dietary intake of saturated fat is associated with reduced semen quality among 701 young Danish men from the general population. Am. J. Clin. Nutr. 2013;97:411-418.
- Чалый М.Е., Ахвледиани Н.Д., Харчилава Р.Р. Мужское бесплодие. Урология. 2016;1 (Прил. 1):2-17
- Загарских Е.Ю., Лабыгина А.В., Курашова Н.А. Опыт лечения нормогонадотропного бесплодия у мужчин. Урология. 2014;5:87-89
- Sigman М. Introduction: Beyond bulk semen parameters. Fertil. Steril. 2014;102:1501
- Лабыгина А.В., Загарских Е.Ю., Сутурина Л.В., Курашова Н.А. Репродуктивное здоровье подростков основных этносов Восточной Сибири, проживающих в сельской местности. Бюллетень ВСНЦ СО РАМН. 2013;92(4):36-40
- Serrano T., Chevrier C., Multigner L., Cordier S., Jégou B. International geographic correlation study of the prevalence of disorders of male reproductive health. Hum. Reprod. 2013;28(7):1974-1986.
- Rolland M., Le Moal J., Wagner V., Royère D., De Mouzon J. Decline in semen concentration and morphology in a sample of 26609 men close to general population between 1989 and 2005 in France. Hum. Reprod. 2013;28:462-470.
- Jensen T., Swan S., Jorgensen N., Toppari J., Redmon B., Punab M., Drobnis E., Haugen T., Zilaitiene B., Sparks A., Irvine D., Wang C., Jouannet P., Brazil C., Paasch U., Salzbrunn A., Skakkebaek N. Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA. Human reproduction. 2014;29(8):1801-1809. doi: 10.1093/humrep/deu118.
- Eisenberg M.L., Li S., Behr B., Cullen M.R., Galusha D., Lamb D.J., Lipshultz L.I. Semen quality, infertility and mortality in the USA. Human reproduction. 2014;29(7): 1567-1574. Doi: 10.1093/ humrep/deu106.
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