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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">101727</article-id><article-id pub-id-type="doi">10.35693/2500-1388-2022-7-2-128-133</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Otorhinolaryngology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оториноларингология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The study of local mucociliary clearance of the middle nasal meatus in clinically healthy individuals and patients with foreign body in the maxillary sinus</article-title><trans-title-group xml:lang="ru"><trans-title>Исследование показателей локального мукоцилиарного клиренса среднего носового хода у клинически здоровых лиц и больных с инородными телами верхнечелюстной пазухи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7240-5651</contrib-id><contrib-id contrib-id-type="scopus">6507950200</contrib-id><contrib-id contrib-id-type="spin">1250-9662</contrib-id><name-alternatives><name xml:lang="en"><surname>Mareev</surname><given-names>Oleg V.</given-names></name><name xml:lang="ru"><surname>Мареев</surname><given-names>Олег Вадимович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, the Head of the Department of otorhinolaryngology</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой оториноларингологии</p></bio><email>ovmareew@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5906-8080</contrib-id><contrib-id contrib-id-type="scopus">23051024200</contrib-id><contrib-id contrib-id-type="researcherid">S-1217-2016</contrib-id><contrib-id contrib-id-type="spin">5502-4395</contrib-id><name-alternatives><name xml:lang="en"><surname>Mareev</surname><given-names>Gleb O.</given-names></name><name xml:lang="ru"><surname>Мареев</surname><given-names>Глеб Олегович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor of the Department of otorhinolaryngology</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры оториноларингологии</p></bio><email>dr-mareev@mail.ru</email><uri>http://www.dr-mareev.ru</uri><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ermakov</surname><given-names>Igor Yu.</given-names></name><name xml:lang="ru"><surname>Ермаков</surname><given-names>Игорь Юрьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>otorhinolaryngologist</p></bio><bio xml:lang="ru"><p>врач-оториноларинголог</p></bio><email>ermakov1988@inbox.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3619-245X</contrib-id><name-alternatives><name xml:lang="en"><surname>Fedosov</surname><given-names>Ivan V.</given-names></name><name xml:lang="ru"><surname>Федосов</surname><given-names>Иван Владленович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate professor, Department of Optics and biophotonics</p></bio><bio xml:lang="ru"><p>канд. физ.-мат. наук, доцент кафедры оптики и биофотоники</p></bio><email>fedosov-optics@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saratov State Medical University named after V.I. Razumovsky</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Саратовский государственный медицинский университет имени В.И. Разумовского» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">SPb Clinical Hospital No.40</institution></aff><aff><institution xml:lang="ru">СПб ГБУЗ «Городская больница №40»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Saratov State University named after N.G. Chernyshevsky</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского» Минобрнауки России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-04-29" publication-format="electronic"><day>29</day><month>04</month><year>2022</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>128</fpage><lpage>133</lpage><history><date date-type="received" iso-8601-date="2022-02-25"><day>25</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-03-25"><day>25</day><month>03</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Mareev O.V., Mareev G.O., Ermakov I.Y., Fedosov I.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Мареев О.В., Мареев Г.О., Ермаков И.Ю., Федосов И.В.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Mareev O.V., Mareev G.O., Ermakov I.Y., Fedosov I.V.</copyright-holder><copyright-holder xml:lang="ru">Мареев О.В., Мареев Г.О., Ермаков И.Ю., Федосов И.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/101727">https://innoscience.ru/2500-1388/article/view/101727</self-uri><abstract xml:lang="en"><p><bold>Aim</bold> – to obtain the values of local mucociliary clearance (MCC) of the middle nasal meatus in normal conditions and in patients with foreign body in the maxillary sinuses.</p> <p><bold>Material and methods.</bold> To assess the local MCC, we used the original method of modern high-speed digital video recording of the microscopic picture of the specimen, followed by its mathematical processing. The study included a group of rhinologically healthy individuals (60 people) and a group of patients with foreign body in the maxillary sinus (90 people).</p> <p><bold>Results. </bold>We obtained the standard values of MCC in rhinologically healthy individuals (11.76 ± 3.01 Hz). In patients with foreign body in the maxillary sinuses, there was a correlation of the local MCC index with the severity of morphological changes, registered by computed tomography (CT), of the paranasal sinuses in the area of the middle nasal meatus and adjacent sinuses. Depending on the results of CT scanning, we identified 3 groups among the patients with foreign bodies in the maxillary sinuses – no morphological changes (CT1), changes outside the ostium (CT2) and pronounced morphological changes in the middle nasal meatus and surrounding paranasal sinuses (CT3). In the CT1 group the average values of the local MCC of the middle nasal meatus were 13.53 ± 2.46 Hz; in group CT2 – 11.71 ± 2.02 Hz; in the CT3 group – 6.84 ± 3.48 Hz. The differences in indicators in groups were statistically significant according to the Mann – Whitney test. The average value of the local MCC of the middle nasal meatus in patients without maxillary sinus mycetoma was 13.30 ± 2.91 Hz, in patients having maxillary sinus mycetoma – 10.74 ± 3.69 Hz; this difference was also statistically significant.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель </bold>– исследование значений локального мукоцилиарного клиренса (МЦК) среднего носового хода в норме и у больных с инородными телами верхнечелюстных пазух.</p> <p><bold>Материал и методы.</bold> Для оценки локального МЦК использован оригинальный метод современной высокоскоростной цифровой видеозаписи микроскопической картины препарата с последующей ее математической обработкой. В исследование вошли группа ринологически здоровых лиц (60 человек) и группа больных с инородными телами верхнечелюстной пазухи (90 человек).</p> <p><bold>Результаты.</bold> Получены нормативные значения МЦК у ринологически здоровых лиц (11,76 ± 3.01 Гц). У больных с инородными телами верхнечелюстных пазух наблюдалась зависимость показателя локального МЦК от выраженности морфологических изменений на компьютерной томографии (КТ) околоносовых пазух в области среднего носового хода и прилежащих пазух. В зависимости от изменений на КТ были выделены 3 группы среди больных с инородными телами верхнечелюстных пазух – с отсутствием изменений (КТ1), изменениями вне области соустья (КТ2) и выраженными морфологическими изменениями в области среднего носового хода и окружающих околоносовых пазух (КТ3). Для группы с изменениями КТ1 средние значения локального МЦК среднего носового хода составили 13,53 ± 2,46 Гц; для группы КТ2 – 11,71 ± 2,02 Гц; для группы КТ3 – 6,84 ± 3,48 Гц. Различия показателей в группах по данным КТ-исследования статистически значимы по критерию Манна – Уитни. Средние значения локального МЦК среднего носового хода у больных без мицетомы верхнечелюстной пазухи составили 13,30 ± 2,91 Гц, с мицетомой верхнечелюстной пазухи – 10,74 ± 3,69 Гц; эти отличия также статистически достоверны.</p></trans-abstract><kwd-group xml:lang="en"><kwd>mucociliary clearance</kwd><kwd>foreign body in maxillary sinus</kwd><kwd>rhinology</kwd><kwd>computed tomography</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>мукоцилиарный клиренс</kwd><kwd>инородные тела верхнечелюстных пазух</kwd><kwd>ринология</kwd><kwd>компьютерная томография</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Sedaghat MH, Shahmardan MM, Norouzi M, et al. Effect of cilia beat frequency on mucociliary clearance. 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