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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">110742</article-id><article-id pub-id-type="doi">10.35693/2500-1388-2022-7-3-148-154</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Human Anatomy</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Анатомия человека</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current data on the development of tongue in prenatal period of human ontogenesis</article-title><trans-title-group xml:lang="ru"><trans-title>Современное представление о развитии и строении языка в пренатальном онтогенезе человека</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2243-3574</contrib-id><name-alternatives><name xml:lang="en"><surname>Alekseeva</surname><given-names>Tatyana A.</given-names></name><name xml:lang="ru"><surname>Алексеева</surname><given-names>Т. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>assistant of the Department of Human Anatomy</p></bio><bio xml:lang="ru"><p>ассистент кафедры анатомии человека</p></bio><email>toncks666@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7401-6502</contrib-id><name-alternatives><name xml:lang="en"><surname>Lutsay</surname><given-names>Elena D.</given-names></name><name xml:lang="ru"><surname>Луцай</surname><given-names>Е. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Department of Human Anatomy</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры анатомии человека</p></bio><email>elut@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Orenburg State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-09-04" publication-format="electronic"><day>04</day><month>09</month><year>2022</year></pub-date><volume>7</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>148</fpage><lpage>154</lpage><history><date date-type="received" iso-8601-date="2022-09-03"><day>03</day><month>09</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-09-03"><day>03</day><month>09</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Alekseeva T.A., Lutsay E.D.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Алексеева Т.А., Луцай Е.Д.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Alekseeva T.A., Lutsay E.D.</copyright-holder><copyright-holder xml:lang="ru">Алексеева Т.А., Луцай Е.Д.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/110742">https://innoscience.ru/2500-1388/article/view/110742</self-uri><abstract xml:lang="en"><p>The timely diagnosis and treatment of maxillofacial pathologies where the tongue plays an important role requires an accurate description of the organ’s structure and development.</p> <p>The paper presents a review of the current research data on the features of embryonic development, macro- and microanatomy, morphometry and ultrasound anatomy of the human tongue during the prenatal development. The selected papers, published in the Russian and English languages, cover the period of the last decade. We generalized the obtained data using the empirical and theoretical approaches.</p> <p>The macroscopic study of the external structure of the tongue was underrepresented in the current studies, usually performed in combination with morphometry. The studies of histotopograms in combination with histochemical methods were numerous, contributing to the more detailed classification of the tongue development stages. The selected papers focused on the period of human embryonic development and the correlating histological characteristics of the tongue. The morphometric characteristics and the blood supply of the tongue in the prenatal period require further research.</p></abstract><trans-abstract xml:lang="ru"><p>Своевременная диагностика и лечение аномалий органов челюстно-лицевой области требуют точной характеристики строения и развития органов, в том числе языка.</p> <p>Исследование представляет собой обзор современных научных данных об особенностях эмбрионального развития, макро- и микроанатомии, данных морфометрии и ультразвуковой анатомии языка человека в период пренатального развития. Анализировались работы по выбранной теме за последние 10 лет на русском и английском языках. Было использовано эмпирическое и теоретическое обобщение данных.</p> <p>Установлено, что макроскопическое изучение внешнего строения языка в публикациях последних лет проводится ограниченно, в комплексе с морфометрией. Более широко используется изучение гистотопограмм в сочетании с гистохимическими методами, что позволяет расширить классификацию стадий развития языка. В работах освещены вопросы характеристики стадий эмбрионального развития и гистологическая характеристика языка человека в пренатальном периоде развития. Наименее изученными на сегодняшний день являются вопросы морфометрической характеристики, а также кровоснабжение языка в пренатальном периоде развития.</p></trans-abstract><kwd-group xml:lang="en"><kwd>tongue</kwd><kwd>embryology</kwd><kwd>anatomy</kwd><kwd>morphometry</kwd><kwd>intravital imaging</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>язык</kwd><kwd>эмбриология</kwd><kwd>анатомия</kwd><kwd>морфометрия</kwd><kwd>прижизненная визуализация</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Cobourne MT, Iseki S, Birjandi AA, et al. 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