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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">110746</article-id><article-id pub-id-type="doi">10.35693/2500-1388-2022-7-3-170-175</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cardiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Кардиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Promising approaches to early diagnosis of chronic rheumatic heart disease</article-title><trans-title-group xml:lang="ru"><trans-title>Перспективные подходы к ранней диагностике хронической ревматической болезни сердца</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6078-2361</contrib-id><name-alternatives><name xml:lang="en"><surname>Santalova</surname><given-names>Galina V.</given-names></name><name xml:lang="ru"><surname>Санталова</surname><given-names>Г. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Head of the Department of Faculty pediatrics</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующая кафедрой факультетской педиатрии</p></bio><email>g.v.santalova@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6665-1533</contrib-id><name-alternatives><name xml:lang="en"><surname>Garanin</surname><given-names>Andrei A.</given-names></name><name xml:lang="ru"><surname>Гаранин</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Assistant of the Chair of Introduction to internal medicine</p></bio><bio xml:lang="ru"><p>канд. мед. наук, ассистент кафедры пропедевтической терапии</p></bio><email>a.a.garanin@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3501-2354</contrib-id><name-alternatives><name xml:lang="en"><surname>Lebedev</surname><given-names>Petr A.</given-names></name><name xml:lang="ru"><surname>Лебедев</surname><given-names>П. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Head of the Department of Therapy, Institute of Professional Education</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой терапии Института профессионального образования</p></bio><email>p.a.lebedev@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4656-3995</contrib-id><name-alternatives><name xml:lang="en"><surname>Kuzin</surname><given-names>Maksim E.</given-names></name><name xml:lang="ru"><surname>Кузин</surname><given-names>М. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>resident of the Department of Faculty Pediatrics</p></bio><bio xml:lang="ru"><p>ординатор кафедры факультетской педиатрии</p></bio><email>kkide@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0382-3363</contrib-id><name-alternatives><name xml:lang="en"><surname>Tereshina</surname><given-names>Olga V.</given-names></name><name xml:lang="ru"><surname>Терешина</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate professor, Department of Therapy, Institute of Professional Education</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры терапии Института профессионального образования</p></bio><email>o.v.tereshina@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Samara State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-09-04" publication-format="electronic"><day>04</day><month>09</month><year>2022</year></pub-date><volume>7</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>170</fpage><lpage>175</lpage><history><date date-type="received" iso-8601-date="2022-09-03"><day>03</day><month>09</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-09-03"><day>03</day><month>09</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Santalova G.V., Garanin A.A., Lebedev P.A., Kuzin M.E., Tereshina O.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Санталова Г.В., Гаранин А.А., Лебедев П.А., Кузин М.Э., Терешина О.В.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Santalova G.V., Garanin A.A., Lebedev P.A., Kuzin M.E., Tereshina O.V.</copyright-holder><copyright-holder xml:lang="ru">Санталова Г.В., Гаранин А.А., Лебедев П.А., Кузин М.Э., Терешина О.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/110746">https://innoscience.ru/2500-1388/article/view/110746</self-uri><abstract xml:lang="en"><p><bold>Aim</bold> – to determine the prevalence of acute rheumatic fever (ARF) in children and chronic rheumatic heart disease (HRHD) in adults on the example of the Samara region and to propose measures for the early detection and prevention of valvular heart lesions.</p> <p><bold>Material and methods.</bold> The authors cite the material of their own research, indicating a significant prevalence of rheumatic etiology of valvular lesions that required surgical treatment in 2016–2020 in the Samara region. We retrospectively analyzed the prevalence of acute rheumatic fever and chronic rheumatic heart disease in out-patients of a large polyclinic of Samara city.</p> <p><bold>Results.</bold> The study demonstrates the low frequency of acute rheumatic fever in the Russian Federation along with the disproportionately high prevalence of chronic rheumatic heart disease.</p> <p><bold>Conclusion. </bold>It is advisable to supplement the procedure for preventive medical examinations of the underage, has being in force in the territory of the Russian Federation since 2017, by ultrasound examination of the heart for the timely diagnosis of chronic rheumatic heart disease and long-term treatment with benzathine penicillin. In this case, it is also possible to identify previously undiagnosed congenital heart defects and heart diseases that manifest in adolescence.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold> – определить распространенность острой ревматической лихорадки (ОРЛ) у детей и хронической ревматической болезни сердца (ХРБС) у взрослых на примере Самарской области и предложить мероприятия по раннему выявлению и профилактике клапанных поражений сердца.</p> <p><bold>Материал и методы. </bold>Авторы приводят материал собственных исследований, свидетельствующий о значительной распространенности ревматической этиологии клапанных поражений, потребовавших оперативного лечения в 2016–2020 гг. в Самарской области. Проведен ретроспективный анализ распространенности ОРЛ и ХРБС в популяции, прикрепленной к крупной поликлинике г. Самары.</p> <p><bold>Результаты.</bold> В РФ наблюдается низкая частота ОРЛ наряду с непропорционально высокой распространенностью ХРБС.</p> <p><bold>Выводы.</bold> Порядок проведения профилактических медицинских осмотров несовершеннолетних, действующий на территории РФ с 2017 года, целесообразно дополнить УЗИ сердца для своевременной диагностики ХРБС и проведения долговременной терапии бензатина пенициллином. В этом случае предоставляется возможность выявления ранее не диагностированных врожденных пороков сердца и болезней сердца, манифестирующих в подростковом возрасте.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute rheumatic fever</kwd><kwd>chronic rheumatic heart disease</kwd><kwd>echocardiography</kwd><kwd>valvular heart disease</kwd><kwd>preventive treatment with benzathine penicillin</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острая ревматическая лихорадка</kwd><kwd>хроническая ревматическая болезнь сердца</kwd><kwd>эхокардиография</kwd><kwd>клапанные пороки сердца</kwd><kwd>профилактика бензатина пенициллином</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>He VY, Condon JR, Ralph AP, et al. Long-Term Outcomes From Acute Rheumatic Fever and Rheumatic Heart Disease: A Data-Linkage and Survival Analysis Approach. 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