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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">112257</article-id><article-id pub-id-type="doi">10.35693/2500-1388-2023-8-1-29-33</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cardiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Кардиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The management of patients aged 90 years and older with ST-segment elevation myocardial infarction</article-title><trans-title-group xml:lang="ru"><trans-title>Выбор оптимальной тактики ведения пациентов с инфарктом миокарда с подъемом сегмента ST в возрастной группе старше 90 лет</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2773-1682</contrib-id><name-alternatives><name xml:lang="en"><surname>Duplyakova</surname><given-names>Polina D.</given-names></name><name xml:lang="ru"><surname>Дуплякова</surname><given-names>Полина Дмитриевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Postgraduate Student of the Department of Cardiology and Cardiovascular Surgery; Cardiologist</p></bio><bio xml:lang="ru"><p>аспирант кафедры кардиологии и сердечно-сосудистой хирургии; врач-кардиолог</p></bio><email>polina_duplyakova@yahoo.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3301-1577</contrib-id><name-alternatives><name xml:lang="en"><surname>Pavlova</surname><given-names>Tatyana V.</given-names></name><name xml:lang="ru"><surname>Павлова</surname><given-names>Татьяна Валентиновна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor of the Department of Cardiology and Cardiovascular Surgery of the Institute of Postgraduate Education; Head of Clinical Research Department</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры кардиологии и сердечно-сосудистой хирургии ИПО; заведующая отделением клинических исследований</p></bio><email>t.v.pavlova@samsmu.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6000-620X</contrib-id><name-alternatives><name xml:lang="en"><surname>Khokhlunov</surname><given-names>Sergey M.</given-names></name><name xml:lang="ru"><surname>Хохлунов</surname><given-names>Сергей Михайлович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Head of the Department of Cardiology and Cardiovascular Surgery of the Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой кардиологии и сердечно-сосудистой хирургии ИПО</p></bio><email>s.m.khokhlunov@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6453-2976</contrib-id><name-alternatives><name xml:lang="en"><surname>Duplyakov</surname><given-names>Dmitry V.</given-names></name><name xml:lang="ru"><surname>Дупляков</surname><given-names>Дмитрий Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Head of the Department of Propaedeutic Therapy; Deputy Chief Physician for Medical Affairs</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой пропедевтической терапии; заместитель главного врача по медицинской части</p></bio><email>duplyakov@yahoo.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Samara State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Samara Regional Clinical Cardiology Dispensary named after V.P. Polyakov</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Самарский областной клинический кардиологический диспансер имени В.П. Полякова»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-02-11" publication-format="electronic"><day>11</day><month>02</month><year>2023</year></pub-date><volume>8</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>29</fpage><lpage>33</lpage><history><date date-type="received" iso-8601-date="2022-10-31"><day>31</day><month>10</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-12-13"><day>13</day><month>12</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Duplyakova P.D., Pavlova T.V., Khokhlunov S.M., Duplyakov D.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Дуплякова П.Д., Павлова Т.В., Хохлунов С.М., Дупляков Д.В.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Duplyakova P.D., Pavlova T.V., Khokhlunov S.M., Duplyakov D.V.</copyright-holder><copyright-holder xml:lang="ru">Дуплякова П.Д., Павлова Т.В., Хохлунов С.М., Дупляков Д.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/112257">https://innoscience.ru/2500-1388/article/view/112257</self-uri><abstract xml:lang="en"><p><bold>Aim</bold> – to study in-hospital outcomes in patients with ST-segment elevation myocardial infarction (STEMI) in the age group over 90 years old, depending on the treatment tactics.</p> <p><bold>Material and methods.</bold> For the period of January, 2017 - December, 2020, in total 72 patients aged ≥ 90 were hospitalized in Samara Regional Clinical Cardiology Dispensary with STEMI: mean age 91.8 years (90-96), among them 49 women (68%). Patients were divided into two groups depending on the chosen treatment strategy. Group 1 included patients (n = 13) who underwent coronary angiography and primary percutaneous coronary intervention (pPCI), mean age 90.6 (90-91) years, 8 women (61.5%). Group 2 included patients who received coronary angiography and conservative treatment (n = 5) and only conservative treatment (n = 54), mean age 91.9 (91-96) years, 41 women (69.5%).</p> <p><bold>Results. </bold>In terms of the incidence of pulmonary edema and cardiogenic shock, both groups were comparable, no statistically significant differences were found. In-hospital mortality among STEMI patients aged 90 years and older was higher in the conservative treatment group than in the invasive group (45.8% vs. 7.7%) (OR 10.12; 95% CI (1.24–82 .96)).</p> <p><bold>Conclusion.</bold> The results obtained in our study may indicate the advantage of the invasive strategy in the treatment of patients with STEMI over the age of 90 years. Further prospective studies based on the principles of evidence-based medicine are required.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold> – изучение госпитальных исходов у пациентов с ИМпST старше 90 лет в зависимости от тактики ведения.</p> <p><bold>Материал и методы.</bold> За период 01.2017‒12.2020 гг. в Самарский областной кардиологический диспансер им. В.П. Полякова было госпитализировано 72 пациента с диагнозом ИМпST в возрастной группе старше 90 лет, средний возраст 91,8 года (90‒96), женщин 49 (68%). Пациенты были разделены на две группы в зависимости от выбранной стратегии ведения. Группа 1 включала пациентов с проведенным пЧКВ (n=13), средний возраст 90,6 (90‒91) года, женщин 8 (61,5%). В группу 2 вошли пациенты с проведенной КГ (n=5) и консервативной тактикой ведения (n=54), средний возраст 91,9 (91‒96) года, женщин 41 (69,5%).</p> <p><bold>Результаты</bold>. По частоте развития отека легких и кардиогенного шока обе группы были сопоставимы, статистически значимых различий выявлено не было. Госпитальная летальность среди пациентов с ИМпSTв возрасте 90 лет и старше была выше в группе консервативной стратегии по сравнению с группой инвазивной тактики ‒ 45,8% против 7,7% (ОШ 10,12; 95% ДИ (1,24‒82,96)).</p> <p><bold>Выводы</bold>. Результаты свидетельствуют о преимуществе инвазивной тактики ведения пациентов с ИМпST в возрасте старше 90 лет. Требуется дальнейшее проведение проспективных исследований, построенных на принципах доказательной медицины.</p></trans-abstract><kwd-group xml:lang="en"><kwd>STEMI</kwd><kwd>reperfusion therapy</kwd><kwd>elderly</kwd><kwd>nonagenarians</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ИМпST</kwd><kwd>реперфузионная терапия</kwd><kwd>пожилые</kwd><kwd>девяностолетние</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Rosstat data as of 06.22.2019. (In Russ.). [Данные Росстата на 22.06.2019]. URL: https://www.gsk.ru</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2020 Clinical practice guidelines for Acute ST-segment elevation myocardial infarction. (RSC) Russian Society of Cardiology. (In Russ.). [Острый инфаркт миокарда с подъемом сегмента ST электрокардиограммы. Клинические рекомендации 2020. Российское кардиологическое общество, Ассоциация сердечно-сосудистых хирургов России. 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