Science and Innovations in MedicineScience and Innovations in Medicine2500-13882618-754XFSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation2154610.35693/2500-1388-2016-0-3-62-66Research ArticleUSING VIRTUAL REALITY AS A METHOD OF ACCELERATED REHABILITATION AMONG THE PATIENTS AFTER STROKEZakharovA VPhD, associate professor of the Department of neurology and neurosurgery, head of the Laboratory of neurointerface of the Center for breakthrough research «IT in Medicine», Samara State Medical University.zakharov1977@mail.ruPyatinV FPhD, professor, head of the Department of physiology with the course of life safety, head of the Department of neurointerfaces and applied neurophysiology of the Center for breakthrough research «IT in Medicine», Samara State Medical University.pyatin_vf@list.ruKolsanovA VPhD, professor, head of the Department of surgery, clinical anatomy with the course of innovative technologies, head of the Center for breakthrough research «IT in Medicine», Samara State Medical University.avkolsanov@mail.ruPoverennovaI EPhD, professor, head of the Department of neurology and neurosurgery of Samara State Medical University.ipover555@mail.ruSegreevaM SPhD, associate professor of the Department of physiology with the course of life safety, head of the Laboratory of applied neurophysiology of the Center for breakthrough research «IT in Medicine», Samara State Medical University.marsergr@yandex.ruKhivintsevaE VPhD, associate professor of the Department of neurology and neurosurgery of Samara State Medical University.elena.v.kh@mail.ruKorovinaE Spostgraduate student at the Department of physiology with the course of life safety of Samara State Medical University.korovina_ekateri@mail.ruKucepalovaG Udoctor of functional diagnostics at Samara regional hospital n.a. V.D. Seredavin.samaranevr@mail.ruSamara State Medical UniversityCenter for breakthrough research «IТ in Medicine» SSMUCenter for breakthrough research «!Т in Medicine» SSMUSamara regional hospital n.a. V.D. Seredavin1509201613626610032020Copyright © 2016, Zakharov A.V., Pyatin V.F., Kolsanov A.V., Poverennova I.E., Segreeva M.S., Khivintseva E.V., Korovina E.S., Kucepalova G.U.2016Aim - exploring the effect of displaying the motion from the first-person’s point of view in virtual reality on the recovery of motor disorders among patients in the acute period of cerebrovascular disorder. Materials and methods. 45 patients with acute cerebrovascular disorder aged 58±7 years were analyzed. Patients were randomized in two groups. The first group received either standard rehabilitation or training with virtual reality equipment. The second group received only standard rehabilitation. Training included displaying the motion from the first-person’s point of view in the virtual reality during 3-7 sessions, 15 minutes each. In this exercise a patient could see his “virtual legs”. Speed range was 2-5 km/h. Berg’s balance assessment was used to score movement function (14 questions, where max score - 56 points - means that there is no dysfunction to notice). Assessment method for comparing groups with unusual distribution (Mann-Whitney criteria) was used as statistical analysis. Results. Exercises with the virtual reality equipment show their efficiency on 15th-19th day after stroke. The most significant outcome can be achieved in 5-9 days after stroke (p=0,022). The rate of movement function recovery depends on the duration of training (p=0,001); the highest outcome can be achieved during the first 3-5 sessions. Conclusion. Additional exercises with the virtual reality equipment help to improve outcomes of movement function recovery among patients with acute cerebrovascular disorder.virtual realitycentral paresisstrokemovement rehabilitationвиртуальная реальностьцентральный парезинсультдвигательная реабилитация[Van den Broek M.D. Why does neurorehabilitation fail? J Head Trauma Rehabil. 2005;982:464- 473][Krishnamurthi RV, Feigin VL, Forouzanfar MH, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson LM, Truelsen T, O'donnell M, Venketasubramanian N, Barker-Collo S, Lawes CM, Wang W, Shinohara Y, Witt E, Ezzati M, Naghavi M, Murray C. Global Burden of Diseases, I.R.F.S., and Group, G.B.D.S.E. . Global and regional burden of first-ever is chaemic and haemorrhagic stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet Glob Health 1, 2013;80:259-281. doi: 10.1016/S2214-109X(13)70089-5][Nakayama H, Jorgensen HS, Raaschou HO, Olsen TS. Recovery of upper extremity function in stroke patients: the Copenhagen Stroke Study. Arch Phys Med Rehabil.1994;75:394-398][Moreira MC, De Amorim Lima AM, Ferraz KM, Benedetti Rodrigues MA. Use of virtual reality in gait recovery among post stroke patients-- A systematic literature review. Disability and Rehabilitation: Assistive Technology. 2013;8:357-362. doi: 10.3109/17483107.2012.749428][Lohse KR, Hilderman CG, Cheung KL, Tatla S., Van Der Loos HF. Virtual reality therapy for adults post-stroke: a systematic review and meta-analysis exploring virtual environments and commercial games in therapy. PLoS One. 2014;(9):93318. doi: 10.1371/journal.pone.0093318][Thomson K, Pollock A, Bugge C, Brady M. Commercial gaming devices for stroke upper limb rehabilitation: a systematic review. Int J Stroke. 2014;9:479-488. doi: 10.1111/ijs.12263][Laver K, George S, Thomas S, Deutsch JE, Crotty M. Virtual reality for stroke rehabilitation: an abridged version of a Cochrane review. Eur J Phys Rehabil Med. 2014;51:497-820. doi: 10.1002/14651858.CD008349.pub3.][Levin M, Magdalon EC, Michaelsen SM, Quevedo A. Quality of Grasping and the Role of Haptics in a 3D Immersive Virtual Reality Environment in Individuals With Stroke. IEEE Trans Neural Syst Rehabil Eng. 2015. doi: 10.1109/ TNSRE.2014.2387412][Bower KJ, Louie J, Landesrocha Y, Seedy P, Gorelik A, Bernhardt J. Clinical feasibility of interactive motion-controlled games for stroke rehabilitation. J Neuroeng Rehabil. 2015;12:63. doi: 10.1186/s12984-015-0057-x][Пятин В.Ф., Колсанов А.В., Сергеева М.С., Захаров А.В., Антипов О.И., Коровина Е.С., Тюрин Н.Л., Глазкова Е.Н. Информационные возможности использования мю- и бета-ритмов ЭЭГ доминантного полушария в конструировании нейрокомпьютерного интерфейса. Фундаментальные исследования. 2015;2(5):975-978][Хивинцева Е.В., Сергеева М.С., Пятин В.Ф., Колсанов А.В., Захаров А.В., Антипов О.И., Коровина Е.С. Динамика сенсомоторной активности коры головного мозга при интенции движения. Нейрокомпьютеры: разработка, применение. 2016;(6):40-43][Сергеева М.С., Пятин В.Ф., Колсанов А.В., Захаров А.В., Антипов О.И., Коровина Е.С. Модуляция сенсомоторных ритмов ЭЭГ. Биомедицинская радиоэлектроника. По материалам XII Международного междисциплинарного конгресса и Научной школы «Нейронаука для медицины и психологии. Новейшие разработки в фундаментальных и прикладных нейроисследованиях и психологии». 2016;5(2):28-30]