Science and Innovations in MedicineScience and Innovations in Medicine2500-13882618-754XFSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation4375110.35693/2500-1388-2019-4-4-21-24Research ArticleFeatures of microcirculation and effectiveness of conservative therapy in exacerbation of chronic tonsillitisOvchinnikovAndrey Y.<p>PhD, Professor, the Head of the Department of otorhinolaryngology</p>mail@msmsu.ruhttps://orcid.org/0000-0002-7262-1151BurenkovEvgenii S.<p>deputy director of clinical work</p>mail@reaviz.ruA.I. Yevdokimov Moscow State University of Medicine and DentistryLLC Mirazh1512201944212408092020Copyright © 2019, Ovchinnikov A.Y., Burenkov E.S.2019<p><strong>Objectives</strong> to study the characteristics of microcirculation in patients with chronic tonsillitis, caused by<em>Streptococcus pyogenes,</em>with confirmed sensitivity to the group of inhibitor-protected penicillins.</p>
<p><strong>Material and methods.</strong>The study of micro vascular blood flow in the tonsils was performed with laser Doppler flowmetry, using the multifunctional diagnostic complex "LAKK-M" (Russia, 2010).</p>
<p><strong>Results.</strong>The analysis of the microcirculation parameters of patients in group I showed significant changes in the functioning of their micro vascular blood flow, if compared to patients in the control group. The intensity of blood flow in the tonsils was significantly less in the individuals with low sensitivity to antibacterial therapy.</p>
<p><strong>Conclusion.</strong>1. In case of the clinical inefficacy of the antibacterial therapy in patients with microflora, sensitive<em>in vitro</em>to the same antibiotics, it is necessary to study the microcirculation in their tonsils. 2. Perfusion indicators can be used as an additional express-criterion for predicting the effectiveness of the conservative therapy. 3. If there is a significant change in the micro vascular blood flow, it is necessary to consider the possibility of surgical treatment of patients with chronic tonsillitis.</p>chronic tonsillitismicrocirculationclinical efficacyхронический тонзиллитмикроциркуляцияклиническая эффективность[Lysov NA, Supilnikov AA, Pribytkov DL. Computer capillaroscopy in the rehabilitation of patients with obliterating diseases of the arteries of the lower extremities. Innovative technologies of rehabilitation: science and practice. Collection of articles of the II International Scientific Conference. 2019:233–239. (In Russ.). [Лысов Н.А., Супильников А.А., Прибытков Д.Л. Применение компьютерной капилляроскопии в реабилитации пациентов с облитерирующими заболеваниями артерий нижних конечностей. Инновационные технологии реабилитации: наука и практика. Сборник статей II Международной научной конференции. 2019:233–239].][Pribytkov DL, Supilnikov AA, Starostina AA, et al. Assessing the microcirculatory bed of the lower extremities in patients with obliterating endarteritis. Vestnik of Medical Institute ''REAVIZ''. 2018;1(31):58–62]. (In Russ.). [Прибытков Д.Л., Супильников А.А., Старостина А.А. и др. Изучение микроциркуляторного русла на нижних конечностях у пациентов с облитерирующим эндартериитом. Вестник медицинского института «РЕАВИЗ». 2018;1(31):58–62].][Mirzoeva EZ, Portenko EG, Shmatov GP. Informational profile of the diseases of the pharynx: chronic tonsillitis and chronic pharyngitise. Russian Otorhinolaryngology. 2015;3(76):84–94. (In Russ.). [Мирзоева Е.З., Портенко Е.Г., Шматов Г.П. Информационный профиль заболеваний глотки: хронического тонзиллита и хронического фарингита. Российская оториноларингология. 2015;3(76):84–94].][Brin AV, Tokar VB, Mirzoeva EZ. Surgery characteristics of the symptoms of chronic tonsillitis and chronic pharingitise for improving their differential diagnostics. Tver Medical Journal. 2016;2:41–44. (In Russ.). [Брин А.В., Токарь В.Б., Мирзоева Е.З. Операционные характеристики симптомов хронического тонзиллита и хронического фарингита для усовершенствования их дифференциальной диагностики. Тверской медицинский журнал. 2016;2:41–44].][Kuznetsova VS, Kholodina OS, Mirzoeva EZ, Vashnevskaya NA. Diagnostic assessment of the significance of the symptoms of chronic tonsillitis and chronic pharyngitise through information technology. Tver Medical Journal. 2018;5:39–40. (In Russ.). [Кузнецова В.С., Холодина О.С., Мирзоева Е.З., Вашневская Н.А. Оценка диагностикой значимости симптомов хронического тонзиллита и хронического фарингита посредством информационных технологий. Тверской медицинский журнал. 2018;5:39–40].]