Science and Innovations in MedicineScience and Innovations in Medicine2500-13882618-754XFSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation5306610.35693/2500-1388-2020-5-4-245-250Research ArticlePrediction of ischemic stroke outcome during thrombolytic therapyMininaYu. D.<p>neurologist</p>jminina1988@gmail.comhttps://orcid.org/0000-0002-2992-6451KalininV. A.<p>PhD, Professor of Department of neurology and neurosurgery</p>jminina1988@gmail.comhttps://orcid.org/0000-0003-3233-8324Samara Regional Clinical Hospital named after V.D. SeredavinSamara State Medical University07122020542452500612202006122020Copyright © 2020, Minina Y.D., Kalinin V.A.2020<p>The problem of ischemic stroke in the Russian Federation occupies a leading place in the structure of causes of mortality. Among all treatment methods, the systemic thrombolytic therapy with a recombinant tissue plasminogen activator is regarded as the most effective one.</p>
<p>This review focuses on clinical studies of the safety and effectiveness of this type of treatment, as well as on prognostically unfavorable factors inducing the hemorrhagic transformation of ischemic stroke.</p>ischemic strokesystemic thrombolytic therapypredictorshemorrhagic transformationишемический инсультсистемная тромболитическая терапияпредикторыгеморрагическая трансформация