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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">624503</article-id><article-id pub-id-type="doi">10.35693/SIM624503</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cardiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Кардиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Extrasystolic arrhythmia as an atrial fibrillation predictor</article-title><trans-title-group xml:lang="ru"><trans-title>Экстрасистолия как предиктор развития фибрилляции предсердий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8753-9700</contrib-id><name-alternatives><name xml:lang="en"><surname>Kunts</surname><given-names>Luiza D.</given-names></name><name xml:lang="ru"><surname>Кунц</surname><given-names>Луиза Дмитриевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>specialist of International Centre for Education and Research in Cardiovascular Pathology and Cardiovisualization</p></bio><bio xml:lang="ru"><p>специалист МНОЦ кардиоваскулярной патологии и кардиовизуализации</p></bio><email>l.d.kunts@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4833-4563</contrib-id><name-alternatives><name xml:lang="en"><surname>Germanova</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Германова</surname><given-names>Ольга А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate professor, Director of International Centre for Education and Research in Cardiovascular Pathology and Cardiovisualization</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент, директор МНОЦ кардиоваскулярной патологии и кардиовизуализации</p></bio><email>o.a.germanova@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9041-4885</contrib-id><name-alternatives><name xml:lang="en"><surname>Reshetnikova</surname><given-names>Yuliya B.</given-names></name><name xml:lang="ru"><surname>Решетникова</surname><given-names>Юлия Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Vice director of International Centre for Education and Research in Cardiovascular Pathology and Cardiovisualization</p></bio><bio xml:lang="ru"><p>заместитель директора МНОЦ кардиоваскулярной патологии и кардиовизуализации</p></bio><email>yu.b.reshetnikova@samsmu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8001-1249</contrib-id><name-alternatives><name xml:lang="en"><surname>Galati</surname><given-names>Giuseppe</given-names></name><name xml:lang="ru"><surname>Галати</surname><given-names>Дж.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>senior consultant cardiologist – heart failure and cardiomyopathies specialist at division of cardiology, cardiovascular department, Senior researcher at the International Centre for Education and Research in Cardiovascular Pathology and Cardiovisualization</p></bio><bio xml:lang="ru"><p>старший консультант-кардиолог – специалист по сердечной недостаточности и кардиомиопатиям отделения кардиологии сердечно-сосудистого отделения, главный специалист МНОЦ кардиоваскулярной патологии и кардиовизуализации</p></bio><email>giuseppe.galati5@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5649-5637</contrib-id><name-alternatives><name xml:lang="en"><surname>Milevskaya</surname><given-names>Irina V.</given-names></name><name xml:lang="ru"><surname>Милевская</surname><given-names>Ирина В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, director</p></bio><bio xml:lang="ru"><p>канд. мед. наук, директор</p></bio><email>mncokpk@samsmu.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6103-8510</contrib-id><name-alternatives><name xml:lang="en"><surname>Biondi-Zoccai</surname><given-names>Giuseppe</given-names></name><name xml:lang="ru"><surname>Бьонди-Дзокай</surname><given-names>Дж.</given-names></name></name-alternatives><address><country country="IT">Italy</country></address><bio xml:lang="en"><p>MD, Associate professor</p></bio><bio xml:lang="ru"><p>доктор медицины, ассоциированный профессор</p></bio><email>giuseppe.biondizoccai@uniroma1.it</email><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Samara State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">I.R.C.C.S. Ospedale Multimedica – Cardiovascular Scientific Institute</institution></aff><aff><institution xml:lang="ru">Институт научных исследований сердечно-сосудистых заболеваний «Мультимедика»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Medical Center Samarskii</institution></aff><aff><institution xml:lang="ru">«Медицинский центр Самарский» ООО «Арника»</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Sapienza University of Rome</institution></aff><aff><institution xml:lang="ru">Сапиенца – Римский университет</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-04-26" publication-format="electronic"><day>26</day><month>04</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-06-03" publication-format="electronic"><day>03</day><month>06</month><year>2024</year></pub-date><volume>9</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>117</fpage><lpage>123</lpage><history><date date-type="received" iso-8601-date="2024-01-10"><day>10</day><month>01</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-04-01"><day>01</day><month>04</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Kunts L.D., Germanova O.A., Reshetnikova Y.B., Galati G., Milevskaya I.V., Biondi-Zoccai G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Кунц Л.Д., Германова О.А., Решетникова Ю.Б., Галати Д., Милевская И.В., Бьонди-Дзокай Д.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Kunts L.D., Germanova O.A., Reshetnikova Y.B., Galati G., Milevskaya I.V., Biondi-Zoccai G.</copyright-holder><copyright-holder xml:lang="ru">Кунц Л.Д., Германова О.А., Решетникова Ю.Б., Галати Д., Милевская И.В., Бьонди-Дзокай Д.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/624503">https://innoscience.ru/2500-1388/article/view/624503</self-uri><abstract xml:lang="en"><p>There is a number of conflicting data regarding electrocardiographic predictors of atrial fibrillation, among which extrasystoles (ES) stand out, but there is no reliable data on which extrasystoles variants may be considered as a risk factor.</p> <p>To identify the relationship between extrasystoles and atrial fibrillation, we have analyzed 3927 publications, from which we identified 46 works relevant for the topic.</p> <p>The data obtained allows us to consider extrasystole as one of the main predictors of the development of atrial fibrillation. An increase in the number of supraventricular and ventricular ES in the anamnesis of patients with atrial fibrillation indicates their relationship.</p></abstract><trans-abstract xml:lang="ru"><p>Имеется ряд противоречивых работ в отношении электрокардиографических предикторов фибрилляции предсердий, среди которых авторами выделяются экстрасистолии, однако достоверных данных о том, какие варианты экстрасистолии могут относиться к факторам риска, нет.</p> <p>Для выявления взаимосвязи между экстрасистолией и фибрилляцией предсердий авторами было проанализировано 3927 публикаций, из которых выделено 46 работ, подходящих под указанную тематику.</p> <p>Полученные данные позволяют рассматривать экстрасистолию как один из основных предикторов развития фибрилляции предсердий. Рост числа наджелудочковых и желудочковых экстрасистолий в анамнезе пациентов с фибрилляцией предсердий свидетельствует о их взаимосвязи.</p></trans-abstract><kwd-group xml:lang="en"><kwd>extrasystole</kwd><kwd>atrial fibrillation</kwd><kwd>predictor of atrial fibrillation</kwd><kwd>risk factors for atrial fibrillation</kwd><kwd>rhythm disturbance</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>экстрасистолия</kwd><kwd>фибрилляция предсердий</kwd><kwd>предиктор фибрилляции предсердий</kwd><kwd>факторы риска фибрилляции предсердий</kwd><kwd>нарушение ритма</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Stewart S, Hart CL, Hole DJ, et al. Population prevalence, incidence, and predictors of atrial fibrillation in the Renfrew/Paisley study. Heart. 2001;86:516-521. https://doi.org/10.1136/heart.86.5.516</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285:2370-2375. https://doi.org/10.1001/jama.285.18.2370</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Miyasaka Y, Barnes ME, Gersh BJ, et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation. 2006;114:119-125. https://doi.org/10.1161/CIRCULATIONAHA.105.595140</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Heeringa J, van der Kuip DA, Hofman A, et al. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006;27:949-953. https://doi.org/10.1093/eurheartj/ehi825</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Naccarelli GV, Varker H, Lin J, et al. Increasing prevalence of atrial fibrillation and flutter in the United States. Am J Cardiol. 2009;104:1534-1539. https://doi.org/10.1016/j.amjcard.2009.07.022</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Fried LP, Borhani NO, Enright P, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol. 1991;1(3):263-76. https://doi.org/10.1016/1047-2797(91)90005-w</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Chauvin M, Brechenmacher C. Atrial refractory periods after atrial premature beats in patients with paroxysmal atrial fibrillation. Pacing Clin Electrophysiol. 1989;12(7 Pt 1):1018-26. https://doi.org/10.1111/j.1540-8159.1989.tb01919.x</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Sideris DA, Toumanidis ST, Tselepatiotis E, et al. Atrial pressure and experimental atrial fibrillation. Pacing Clin Electrophysiol. 1995;18(9 Pt 1):1679-85. https://doi.org/10.1111/j.1540-8159.1995.tb06989.x</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Haissaguerre M, Jais P, Shah D.C, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339:659-666. https://doi.org/10.1056/NEJM199809033391003</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Peinado R, Merino JL, Gnoatto M, et al. Atrial fibrillation triggered by postinfarction ventricular premature beats in a patient with Wolff-Parkinson-White syndrome. Europace. 2005;7:221-224. https://doi.org/10.1016/j.eupc.2004.12.003</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Schwieler JH, Zlochiver S, Pandit SV, et al. Reentry in an accessory atrioventricular pathway as a trigger for atrial fibrillation initiation in manifest Wolff-Parkinson-White syndrome: a matter of reflection? Heart Rhythm. 2008;5:1238-1247. https://doi.org/10.1016/j.hrthm.2008.05.028</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Bocchese M, Mangrolia H, Basil A, et al. Atrial fibrillation triggered by premature ventricular complexes: an under-recognized trigger. JACC Case Rep. 2020;2:2244-2248. https://doi.org/10.1016/j.jaccas.2020.09.048</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Guo YH, Liu QM, Qi SS, et al. Characterizations of atrial contractions triggering paroxysmal atrial fibrillation and the effect of atrial fibrillation prevention pacing. 2007;32(2):337-40. Chinese. PMID: 17478949</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Marcus GM. Evaluation and management of premature ventricular complexes. Circulation. 2020;141:1404-1418. https://doi.org/10.1161/CIRCULATIONAHA.119.042434</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Latchamsetty R, Bogun F. Premature ventricular complexes and premature ventricular complex induced cardiomyopathy. Curr Probl Cardiol. 2015;40:379-422. https://doi.org/10.1016/j.cpcardiol.2015.03.002</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Lacharite-Roberge AS, Hoffmayer KS. Premature Ventricular Contractions and Atrial Fibrillation: The Reunion of Distant Relatives? J Am Heart Assoc. 2023;12(4):e029117. https://doi.org/10.1161/JAHA.123.029117</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339:659-666. https://doi.org/10.1056/NEJM199809033391003</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Folkeringa RJ, Hartgers J, Tieleman RG, et al. Atrial extrasystoles after exercise predict atrial fibrillation in patients with left ventricular hypertrophy. Heart. 2006;92(4):545-6. https://doi.org/10.1136/hrt.2005.069542</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Vincenti A, Brambilla R, Fumagalli MG, et al. Onset mechanism of paroxysmal atrial fibrillation detected by ambulatory Holter monitoring. Europace. 2006;8(3):204-10. https://doi.org/10.1093/europace/euj043</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Watanabe H, Tanabe N, Makiyama Y, et al. ST-segment abnormalities and premature complexes are predictors of new-onset atrial fibrillation: the Niigata preventive medicine study. Am Heart J. 2006;152(4):731-5. https://doi.org/10.1016/j.ahj.2006.05.032</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Kinoshita S, Katoh T. Paroxysmal atrial fibrillation initiated by late coupled atrial extrasystoles. J Cardiovasc Med (Hagerstown). 2007;8(11):940-2. https://doi.org/10.2459/JCM.0b013e3280127b2b</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Perez MV, Dewey FE, et al. Electrocardiographic predictors of atrial fibrillation. Am Heart J. 2009;158(4):622-8. https://doi.org/10.1016/j.ahj.2009.08.002</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Jidéus L, Kesek M, Joachimsson PO, et al. The role of premature atrial contractions as the main triggers of postoperative atrial fibrillation. J Electrocardiol. 2006;39(1):48-54. https://doi.org/10.1016/j.jelectrocard.2005.07.010</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Johnson LS, Juhlin T, Juul-Moller S, et al. A prospective study of supraventricular activity and incidence of atrial fibrillation. Heart Rhythm. 2015;12:1898-904. https://doi.org/10.1016/j.hrthm.2015.04.042</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Acharya T, Tringali S, Bhullar M, et al. Frequent Atrial Premature Complexes and Their Association With Risk of Atrial Fibrillation. Am J Cardiol. 2015;116(12):1852-7. https://doi.org/10.1016/j.amjcard.2015.09.025</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Larsen BS, Kumarathurai P, Falkenberg J, et al. Excessive Atrial Ectopy and Short Atrial Runs Increase the Risk of Stroke Beyond Incident Atrial Fibrillation. J Am Coll Cardiol. 2015;66(3):232-241. https://doi.org/10.1016/j.jacc.2015.05.018</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Suzuki S, Sagara K, Otsuka T, et al. Usefulness of frequent supraventricular extrasystoles and a high CHADS2 score to predict first-time appearance of atrial fibrillation. Am J Cardiol. 2013;111(11):1602-7. https://doi.org/10.1016/j.amjcard.2013.01.335</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Kim IS, Yang PS, Kim TH, et al. Clinical Significance of Additional Ablation of Atrial Premature Beats after Catheter Ablation for Atrial Fibrillation. Yonsei Med J. 2016;57(1):72-80. https://doi.org/10.3349/ymj.2016.57.1.72</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Christensen MA, Nguyen KT, Stein PK, et al. Atrial ectopy as a mediator of the association between race and atrial fibrillation. Heart Rhythm. 2017;14(12):1856-1861. https://doi.org/10.1016/j.hrthm.2017.09.034</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Prasitlumkum N, Rattanawong P, Limpruttidham N, et al. Frequent premature atrial complexes as a predictor of atrial fibrillation: Systematic review and meta-analysis. J Electrocardiol. 2018;51(5):760-767. https://doi.org/10.1016/j.jelectrocard.2018.05.012</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Younis A, Nof E, Israel A, et al. Relation of Atrial Premature Complexes During Exercise Stress Testing to the Risk for the Development of Atrial Fibrillation in Patients Undergoing Cardiac Rehabilitation. Am J Cardiol. 2018;122(3):395-399. https://doi.org/10.1016/j.amjcard.2018.04.023</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Kawai S, Mukai Y, Inoue S, et al. Non-pulmonary vein triggers of atrial fibrillation are likely to arise from low-voltage areas in the left atrium. Sci Rep. 2019;9:12271. https://doi.org/10.1038/s41598-019-48669-1</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Himmelreich JCL, Lucassen WAM, Heugen M, et al. Frequent premature atrial contractions are associated with atrial fibrillation, brain ischaemia, and mortality: a systematic review and meta-analysis. Europace. 2019;21(5):698-707. https://doi.org/10.1093/europace/euy276</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Todo K, Iwata T, Doijiri R, et al. Frequent Premature Atrial Contractions in Cryptogenic Stroke Predict Atrial Fibrillation Detection with Insertable Cardiac Monitoring. Cerebrovasc Dis. 2020;49(2):144-150. https://doi.org/10.1159/000505958</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Durmaz E, Ikitimur B, Kilickiran Avci B, et al. The clinical significance of premature atrial contractions: How frequent should they become predictive of new-onset atrial fibrillation. Ann Noninvasive Electrocardiol. 2020;25(3):e12718. https://doi.org/10.1111/anec.12718</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Kim YG, Han KD, Choi JI, et al. Premature ventricular contraction is associated with increased risk of atrial fibrillation: a nationwide population-based study. Sci Rep. 2021;11:1601. https://doi.org/10.1038/s41598-021-81229-0</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Zou F, Di Biase L, Mohanty S, et al. Prevalence of atrial fibrillation and procedural outcome in patients undergoing catheter ablation for premature ventricular complexes. J Cardiovasc Electrophysiol. 2023;34(1):147-152. https://doi.org/10.1111/jce.15749</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Lee PT, Huang MH, Huang TC, et al. High burden of premature ventricular complex increases the risk of new-onset atrial fibrillation. J Am Heart Assoc. 2023;11:e027674. https://doi.org/10.1161/JAHA.122.027674</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Rujirachun P, Wattanachayakul P, Phichitnitikorn P, et al. Risk of atrial fibrillation among patients with premature ventricular complexes: a systematic review and meta-analysis of cohort studies. Minerva Cardiol Angiol. 2023;71(4):381-386. https://doi.org/10.23736/S2724-5683.22.06120-8</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>van Schie MS, Liao R, Ramdat Misier NL, et al. Atrial extrasystoles enhance low-voltage fractionation electrograms in patients with atrial fibrillation. Europace. 2023;25(9):euad223. https://doi.org/10.1093/europace/euad223</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Germanova O, Shchukin Yu, Germanov V, et al. Extrasystolic arrhythmia: is it an additional risk factor of atherosclerosis? Minerva Cardiol Angiol. 2022;70(1):32-39. https://doi.org/10.23736/S2724-5683.20.05490-0</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Germanova OA, Germanov AV, Shchukin YuV. Maximum time between cardiac cycles in atrial fibrillation for assessing the risk of arterial thromboembolism. Russian Journal of Cardiology. 2022;27(7):5007. (In Russ.). [Германова О.А., Германов А.В., Щукин Ю.В. Продолжительность максимального времени между кардиоциклами при фибрилляции предсердий для оценки риска артериальных тромбоэмболических осложнений. Российский кардиологический журнал. 2022;27(7):5007]. https://doi.org/10.15829/1560-4071-2022-5007 EDN YNEQIZ</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Schweikert RA, Perez Lugones A, Kanagaratnam L, et al. A simple method of mapping atrial premature depolarizations triggering atrial fibrillation. Pacing Clin Electrophysiol. 2001;24(1):22-7. https://doi.org/10.1046/j.1460-9592.2001.00022.x</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Kanda T, Masuda M, Fujita M, et al. Comparison of the origin and coupling interval between ectopy with and without atrial fibrillation initiation. J Cardiol. 2018;71(1):59-64. https://doi.org/10.1016/j.jjcc.2017.06.002</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Schmitt C, Ndrepepa G, Weber S, et al. Biatrial multisite mapping of atrial premature complexes triggering onset of atrial fibrillation. Am J Cardiol. 2002;89(12):1381-7. https://doi.org/10.1016/s0002-9149(02)02350-0</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Ndrepepa G, Weber S, Karch MR, et al. Electrophysiologic characteristics of the spontaneous onset and termination of atrial fibrillation. Am J Cardiol. 2002;90(11):1215-20. https://doi.org/10.1016/s0002-9149(02)02837-0</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>Healey JS, Connolly SJ. Atrial fibrillation: hypertension as a causative agent, risk factor for complications, and potential therapeutic target. Am J Cardiol. 2003;91(10A):9G-14G. https://doi.org/10.1016/s0002-9149(03)00227-3</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Yoshida K, Hattori A, Tsuneoka H, et al. Electrophysiological relation between the superior vena cava and right superior pulmonary vein in patients with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol. 2017;28(10):1117-1126. https://doi.org/10.1111/jce.13286</mixed-citation></ref></ref-list></back></article>
