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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">635050</article-id><article-id pub-id-type="doi">10.35693/SIM635050</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Gerontology and geriatrics</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Геронтология и гериатрия</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Changes in quality of life during social isolation in elderly patients with visual impairment</article-title><trans-title-group xml:lang="ru"><trans-title>Изменения качества жизни при социальной изоляции у пожилых пациентов с нарушением зрения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4821-3692</contrib-id><name-alternatives><name xml:lang="en"><surname>Agarkov</surname><given-names>Nikolay M.</given-names></name><name xml:lang="ru"><surname>Агарков</surname><given-names>Н. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor of the Department of Biomedical Engineering</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры биомедицинской инженерии</p></bio><email>anton-titov-2001@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0202-7795</contrib-id><name-alternatives><name xml:lang="en"><surname>Popova</surname><given-names>Natalia V.</given-names></name><name xml:lang="ru"><surname>Попова</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>ophthalmologist Laser surgery department</p></bio><bio xml:lang="ru"><p>врач-офтальмолог отделения лазерной хирургии</p></bio><email>mntk@mntk-tambov.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Southwest State University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Юго-Западный государственный университет» Минобрнауки России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">S.N. Fedorov National medical research center</institution></aff><aff><institution xml:lang="ru">ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» имени академика С.Н. Федорова» Минздрава России, Тамбовский филиал</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-11-26" publication-format="electronic"><day>26</day><month>11</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2024</year></pub-date><volume>9</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>268</fpage><lpage>271</lpage><history><date date-type="received" iso-8601-date="2024-08-09"><day>09</day><month>08</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-10-22"><day>22</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Agarkov N.M., Popova N.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Агарков Н.М., Попова Н.В.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Agarkov N.M., Popova N.V.</copyright-holder><copyright-holder xml:lang="ru">Агарков Н.М., Попова Н.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/635050">https://innoscience.ru/2500-1388/article/view/635050</self-uri><abstract xml:lang="en"><p><bold>Aim</bold> – to determine the nature of changes in the quality of life in social isolation and risk factors associated with it in elderly patients with visual impairment.</p> <p><bold>Material and methods. </bold>A clinical group was formed of 115 participants with visual impairment aged 60–74 years who were in conditions of social isolation for a month. In accordance with the Helsinki Declaration, social isolation was determined on the basis of a 15-point scale, and a questionnaire on quality of life was used to measure changes in the quality of life. Risk factors included socio-demographic, clinical categories and indicators of functional status.</p> <p><bold>Results.</bold> The results of linear mixed models with random intersections comparing quality of life indicators before (3.30) and after social isolation (1.78) were significant (p&lt;0.001). During social isolation, 87% of participants with visual impairment experienced a decrease in quality of life (-2.39), while 13% of participants had an increase in quality of life (0.58). The following risk factors were associated with social isolation: low income (38%, p&lt;0.001), lack of higher education (29%, p=0.002), lung disease (25%, p=0.04), functional or sensory disorders, including difficulties with cooking (28%, p=0.004), difficulty in walking the distance of one block (26%, p=0.03), hearing impairment (23%, p=0.02) and visual impairment (24%, p=0.01). Gender (p=0.39), ongoing pain (p=0.75), difficulties with daily activities (p=0.09), urinary incontinence (p=0.82), diabetes mellitus (p=0.87) and cognitive impairment (p=0.06) were insignificant.</p> <p><bold>Conclusion. </bold>The period of social isolation led to a very significant decrease in the overall quality of life in the sample of elderly people with visual impairment. The leading risk factors for social exclusion were low income and lack of higher education.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold> – определение характера изменения качества жизни у пожилых пациентов с нарушением зрения при социальной изоляции и связанных с ней факторов риска.</p> <p><bold>Материал и методы.</bold> Была сформирована клиническая группа из 115 участников 60–74 лет с нарушением зрения, находящихся в условиях социальной изоляции в течение месяца. В соответствии с Хельсинкской декларацией социальная изоляция была определена на основе 15-балльной шкалы, опросник качества жизни использовался для измерения изменений в качестве жизни. Факторы риска включали социально-демографические, клинические категории и показатели функционального состояния.</p> <p><bold>Результаты.</bold> Результаты линейных смешанных моделей со случайными пересечениями, сравнивающих показатели качества жизни до (3,30) и после социальной изоляции (1,78), были значимыми (p&lt;0,001). Во время социальной изоляции у 87% участников с нарушением зрения наблюдалось снижение качества жизни (-2,39), тогда как у 13% участников наблюдалось повышение качества жизни (0,58). С социальной изоляцией были связаны следующие факторы риска: низкий уровень доходов (38%, p&lt;0,001), отсутствие высшего образования (29%, p=0,002), заболевание легких (25%, р=0,04), функциональные или сенсорные нарушения, включающие трудности с приготовлением пищи (28%, p=0,004), трудности с прохождением одного квартала (26%, р=0,03), нарушение слуха (23%, р=0,02) и нарушение зрения (24%, p=0,01). Незначимыми оказались пол (р=0,39), текущая боль (р=0,75), трудности с повседневными действиями (p=0,09), недержание мочи (р=0,82), сахарный диабет (p=0,87) и когнитивные нарушения (р=0,06).</p> <p><bold>Заключение. </bold>Период социальной изоляции привел к весьма значительному снижению общего качества жизни в выборке пожилых людей с нарушением зрения. Ведущими факторами риска социальной изоляции оказались низкий уровень доходов и отсутствие высшего образования.</p></trans-abstract><kwd-group xml:lang="en"><kwd>social isolation</kwd><kwd>visual impairment</kwd><kwd>elderly</kwd><kwd>quality of life</kwd><kwd>risk factors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>социальная изоляция</kwd><kwd>нарушение зрения</kwd><kwd>пожилые</kwd><kwd>качество жизни</kwd><kwd>факторы риска</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Holt-Lunstad J, Smith TB, Baker M, et al. 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