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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">688475</article-id><article-id pub-id-type="doi">10.35693/SIM688475</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cardiology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Кардиология</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Possibilities and prospects of echocardiographic diagnostics of regional contractility disorders of the left ventricular myocardium in patients with chronic ischemic heart disease</article-title><trans-title-group xml:lang="ru"><trans-title>Возможности и перспективы эхокардиографической диагностики нарушений локальной сократимости миокарда левого желудочка при хронической ишемической болезни сердца</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1103-5001</contrib-id><name-alternatives><name xml:lang="en"><surname>Nikolaeva</surname><given-names>Tatyana O.</given-names></name><name xml:lang="ru"><surname>Николаева</surname><given-names>Татьяна Олеговна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Associate professor, Head of the Department of internal diseases</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент, заведующая кафедрой пропедевтики внутренних болезней</p></bio><email>nikolaevato@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4818-434X</contrib-id><name-alternatives><name xml:lang="en"><surname>Mazur</surname><given-names>Vera V.</given-names></name><name xml:lang="ru"><surname>Мазур</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Associate professor, Professor the Department of Hospital Therapy and Occupational Diseases</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент, профессор кафедры госпитальной терапии и профессиональных болезней</p></bio><email>vera.v.mazur@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8879-3791</contrib-id><name-alternatives><name xml:lang="en"><surname>Mazur</surname><given-names>Evgenii S.</given-names></name><name xml:lang="ru"><surname>Мазур</surname><given-names>Е. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor, Head of the Department of Hospital Therapy and Occupational Diseases</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующий кафедрой госпитальной терапии и профессиональных болезней</p></bio><email>mazur-tver@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Tver State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Тверской государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-08-12" publication-format="electronic"><day>12</day><month>08</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-08-24" publication-format="electronic"><day>24</day><month>08</month><year>2025</year></pub-date><volume>10</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>201</fpage><lpage>210</lpage><history><date date-type="received" iso-8601-date="2025-07-29"><day>29</day><month>07</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-08-08"><day>08</day><month>08</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Nikolaeva T.O., Mazur V.V., Mazur E.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Николаева Т.О., Мазур В.В., Мазур Е.С.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Nikolaeva T.O., Mazur V.V., Mazur E.S.</copyright-holder><copyright-holder xml:lang="ru">Николаева Т.О., Мазур В.В., Мазур Е.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/688475">https://innoscience.ru/2500-1388/article/view/688475</self-uri><abstract xml:lang="en"><p>Currently, the primary method for identifying transient disorders of local contractility of the left ventricular myocardium in patients with coronary atherosclerosis remains visual assessment of myocardial contractility under physical or pharmacological stress testing. Visual assessment of myocardial contractility, especially in stress tests, requires extensive experience in conducting such studies. However, visual assessment by even the most experienced operator remains subjective. Consequently, a principal focus in diagnosing left ventricular regional wall motion abnormalities has been, and remains, the development of methods for objective quantitative assessment of functional status across different left ventricular myocardial segments. A significant success in this area was the development of speckle-tracking echocardiography technique, which allows for a quantitative assessment of myocardial deformation during its contraction and relaxation.</p> <p>The review presents the results of studies indicating that the determination of left ventricular myocardial deformation indices may become an alternative to the traditional method, devoid of such disadvantages as the subjectivity of visual information perception and very high requirements for the operator’s qualification level. Deepening knowledge about the mechanisms, clinical significance of various myocardial deformation indices, the improvement of both the speckle-tracking echocardiography technique itself and the algorithms of automated processing of data creates a real prospect for its introduction into clinical practice as the main method for identifying transient disorders of local left ventricular contractility in patients with hemodynamically significant coronary atherosclerosis.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время основным методом выявления транзиторных нарушений локальной сократимости миокарда левого желудочка у больных с коронарным атеросклерозом служит визуальная оценка сократимости миокарда при физической или фармакологической нагрузке. Визуальная оценка сократительной способности миокарда, особенно в нагрузочных пробах, требует большого опыта в проведении такого рода исследований. Однако зрительная оценка даже самого опытного оператора по-прежнему не лишена субъективизма. В связи с этим одним из магистральных направлений диагностики нарушений локальной сократимости левого желудочка была и остается разработка методов объективной количественной оценки функционального состояния различных участков миокарда левого желудочка. Существенным успехом на этом пути стало создание методики отслеживания серого пятна (speckle-tracking эхокардиография), позволяющей получить количественную оценку деформации миокарда при его сокращении и расслаблении.</p> <p>В обзоре представлены результаты исследований, свидетельствующие, что определение показателей деформации миокарда левого желудочка может стать альтернативой традиционному методу, лишенной таких его недостатков, как субъективизм восприятия визуальной информации и очень высокие требования к уровню квалификации оператора. Углубление знаний о механизмах и клиническом значении различных показателей деформации миокарда, наряду с совершенствованием как самой методики speckle-tracking эхокардиографии, так и алгоритмов автоматизированной обработки получаемых с ее помощью данных, создает реальную перспективу ее внедрения в клиническую практику в качестве основного метода выявления транзиторных нарушений локальной сократимости миокарда левого желудочка у больных с гемодинамически значимым коронарным атеросклерозом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chronic ischemic heart disease</kwd><kwd>stress-echocardiography</kwd><kwd>speckle tracking echocardiography technology</kwd><kwd>regional myocardial contractility disorders</kwd><kwd>longitudinal systolic deformation of the left ventricle</kwd><kwd>myocardial postsystolic shortening</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хроническая ишемическая болезнь сердца</kwd><kwd>стресс-эхокардиография</kwd><kwd>нарушения локальной сократимости миокарда</kwd><kwd>технология speckle tracking echocardiography</kwd><kwd>продольная систолическая деформация левого желудочка</kwd><kwd>постсистолическое укорочение миокарда</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Lang RM, Badano LP, Mor-Avi V, et al. 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