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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">699914</article-id><article-id pub-id-type="doi">10.35693/SIM699914</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Biomechanical and morphological foundations of the pathogenesis of cubital canal syndrome</article-title><trans-title-group xml:lang="ru"><trans-title>Биомеханические и морфологические основы патогенеза синдрома кубитального канала</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6067-8962</contrib-id><contrib-id contrib-id-type="scopus">57568022200</contrib-id><contrib-id contrib-id-type="researcherid">PDW-9099-2025</contrib-id><contrib-id contrib-id-type="spin">9623-4500</contrib-id><name-alternatives><name xml:lang="en"><surname>Edilgireeva</surname><given-names>Leila</given-names></name><name xml:lang="ru"><surname>Эдильгиреева</surname><given-names>Лейла Арбиевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>аспирант</p></bio><email>snickers_192000@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">First Moscow State Medical University I.M. Sechenov (Sechenov University)</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2026-05-09" publication-format="electronic"><day>09</day><month>05</month><year>2026</year></pub-date><history><date date-type="received" iso-8601-date="2025-12-28"><day>28</day><month>12</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2026-01-16"><day>16</day><month>01</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; , Edilgireeva L.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; , Эдильгиреева Л.А.</copyright-statement><copyright-holder xml:lang="en">Edilgireeva L.</copyright-holder><copyright-holder xml:lang="ru">Эдильгиреева Л.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/699914">https://innoscience.ru/2500-1388/article/view/699914</self-uri><abstract xml:lang="en"><p> </p><p>In the structure of peripheral nervous system disorders, tunnel neuropathies account for about a quarter of all cases, among which cubital tunnel syndrome (CuTS) holds one of the leading positions. A high prevalence of CuTS is noted among individuals of working age with occupational risk factors (repeated flexion/extension, vibration, prolonged pressure on the elbows). This review summarizes epidemiological data and occupational risk factors, anatomical features of the cubital tunnel and biomechanics of the elbow joint that contribute to ulnar nerve compression and the development of CuTS, as well as their role in the formation of the "compression–ischemia–edema" pathophysiological changes leading to subsequent demyelination and axonal damage of the ulnar nerve. Management strategies for patients with CuTS are discussed: early severity stratification, timely surgical decompression (the benchmark is the first 4–6 months for moderate/severe cases), correction of risk factors, and rehabilitation to improve treatment outcomes.</p>  <p> </p><p> </p> </abstract><trans-abstract xml:lang="ru"><p> </p><p>В структуре заболеваний периферической нервной системы около четверти всех случаев составляют туннельные невропатии, среди которых одно из ведущих мест занимает синдром кубитального канала (СКК). Отмечается широкая распространённость СКК среди лиц трудоспособного возраста с профессиональными факторами риска (повторные сгибания/разгибания, вибрация, длительная опора на локти). В обзоре обобщены эпидемиологические данные и профессиональные факторы риска, анатомические особенности строения кубитального канала и биомеханики локтевого сустава, способствующие компрессии локтевого нерва и развитию СКК, их роль в формировании патофизиологических изменений «компрессия—ишемия—отёк» с последующей демиелинизацией и аксональным повреждением локтевого нерва. Обсуждаются вопросы ведения пациентов с СКК: ранняя стратификация тяжести, проведение своевременной хирургической декомпрессии (ориентир — первые 4–6 месяцев при среднетяжёлом/тяжёлом течении), коррекция факторов риска и реабилитация для улучшения исходов лечения. </p>  <p> </p><p> </p> </trans-abstract><kwd-group xml:lang="en"><kwd>Keywords: compression-ischemic neuropathy, ulnar nerve, biomechanics, pathophysiology, diagnosis, surgical treatment.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Ключевые слова:  компрессионно-ишемическая невропатия, локтевой нерв, биомеханика, патофизиология, диагностика, хирургическое лечение.</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.	Cambon-Binder A. Ulnar neuropathy at the elbow. Cambon-Binder A. Orthop Traumatol Surg Res. 2021;Feb;107(1S):102754. DOI: 10.1016/j.otsr.2020.102754</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2.	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