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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Science and Innovations in Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Science and Innovations in Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Наука и инновации в медицине</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2500-1388</issn><issn publication-format="electronic">2618-754X</issn><publisher><publisher-name xml:lang="en">FSBEI of Higher Education SamSMU of Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">701205</article-id><article-id pub-id-type="doi">10.35693/SIM701205</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Oncology and radiotherapy</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Онкология, лучевая терапия</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Geospatial analysis of the incidence of lung cancer in the population of the Republic of Tatarstan and its relationship with natural and anthropogenic factors</article-title><trans-title-group xml:lang="ru"><trans-title>Геопространственный анализ заболеваемости населения Республики Татарстан раком легких и ее связь с природными и антропогенными факторами</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1695-168X</contrib-id><name-alternatives><name xml:lang="en"><surname>Gataullin</surname><given-names>Bulat I.</given-names></name><name xml:lang="ru"><surname>Гатауллин</surname><given-names>Булат Ильгизович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), assistant of the Department of Oncology, Radiology and Palliative.</p></bio><bio xml:lang="ru"><p>канд. мед. наук, ассистент кафедры онкологии, радиологии и паллиативной медицины.</p></bio><email>bulatg@list.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9671-3969</contrib-id><name-alternatives><name xml:lang="en"><surname>Shlychkov</surname><given-names>Anatolii P.</given-names></name><name xml:lang="ru"><surname>Шлычков</surname><given-names>А. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Geography), Senior Researcher at the Institute of Ecology and Natural Resources of the Republic of Tatarstan.</p></bio><bio xml:lang="ru"><p>канд. геогр. наук, старший научный сотрудник Института проблем экологии и природных ресурсов Республики Татарстан.</p></bio><email>shlychkov@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0416-5342</contrib-id><name-alternatives><name xml:lang="en"><surname>Biktemirova</surname><given-names>Raisa G.</given-names></name><name xml:lang="ru"><surname>Биктемирова</surname><given-names>Р. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor of the Department of Human Health Protection.</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры охраны здоровья человека.</p></bio><email>RGBiktemirova@kpfu.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5115-6388</contrib-id><name-alternatives><name xml:lang="en"><surname>Gataullin</surname><given-names>Ilgiz G.</given-names></name><name xml:lang="ru"><surname>Гатауллин</surname><given-names>И. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor of the Department of Oncology, Radiology and Palliative.</p></bio><bio xml:lang="ru"><p>д.м.н., профессор кафедры онкологии, радиологии и паллиативной медицины</p></bio><email>ilgizg@list.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Institute of Fundamental Medicine and Biology, Kazan Federal University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Институт фундаментальной медицины и биологии. Казанский федеральный университет»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kazan State Medical Academy</institution></aff><aff><institution xml:lang="ru">Казанская государственная медицинская академия – филиал ФГБОУ ДПО РМАНПО Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Institute of Ecology and Subsoil Use of the Academy of Sciences of the Republic of Tatarstan</institution></aff><aff><institution xml:lang="ru">Институт проблем экологии и недропользования Академии наук Республики Татарстан</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2026-03-28" publication-format="electronic"><day>28</day><month>03</month><year>2026</year></pub-date><pub-date date-type="pub" iso-8601-date="2026-04-14" publication-format="electronic"><day>14</day><month>04</month><year>2026</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>129</fpage><lpage>135</lpage><history><date date-type="received" iso-8601-date="2026-01-18"><day>18</day><month>01</month><year>2026</year></date><date date-type="accepted" iso-8601-date="2026-02-05"><day>05</day><month>02</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Gataullin B.I., Shlychkov A.P., Biktemirova R.G., Gataullin I.G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Гатауллин Б.И., Шлычков А.П., Биктемирова Р.Г., Гатауллин И.Г.</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Gataullin B.I., Shlychkov A.P., Biktemirova R.G., Gataullin I.G.</copyright-holder><copyright-holder xml:lang="ru">Гатауллин Б.И., Шлычков А.П., Биктемирова Р.Г., Гатауллин И.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://innoscience.ru/2500-1388/article/view/701205">https://innoscience.ru/2500-1388/article/view/701205</self-uri><abstract xml:lang="en"><p><bold>Aim:</bold> to identify patterns of lung cancer incidence in the population of the Republic of Tatarstan and its dependence on air pollution and the cyclicity of solar activity.</p> <p><bold>Material and methods. </bold>The following data were used as initial data: data on lung cancer incidence available in the cancer registry of the Republican Clinical Oncology Dispensary of the Ministry of Health of the Republic of Tatarstan for the period from 2012 to 2021; data on emissions into the atmosphere and concentrations of carcinogens in the atmospheric air, available in the State reports “On the state of the natural environment of the Republic of Tatarstan” of the Ministry of Ecology and Natural Environment of the Republic of Tatarstan.</p> <p><bold>Results.</bold> The study demonstrated a high degree of correlation between the comprehensive index of air pollution with carcinogens (IAPc) and the incidence of lung cancer in the population (r=0.79 at the level of α=0.05). To identify the relationship between the solar activity and the incidence of lung cancer, a statistical analysis of the long-term incidence rate of the population and the level of solar activity was carried out using the relative number of sunspots (Wolf number, W). The correlation factor between W and the incidence of lung cancer is significant at α=0.05, the value being r=0.72, which indicates a noticeable strength of the relationship between the studied indicators.</p> <p><bold>Conclusion. </bold>Improving the monitoring system, monitoring the state of the external environment, and measures to prevent air pollution will help reduce the incidence of cancer, including lung cancer.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель: </bold>выявить закономерности формирования заболеваемости раком легких населения Республики Татарстан и ее зависимость от загрязнения атмосферного воздуха и цикличности солнечной активности.</p> <p><bold>Материал и методы. </bold>В качестве исходных данных использованы следующие материалы: о заболеваемости раком легких, приведенные в канцер-регистре Республиканского клинического онкологического диспансера Минздрава Республики Татарстан за период с 2012 по 2021 гг.; о выбросах в атмосферу и концентрациях канцерогенов в атмосферном воздухе, приведенные в Государственных докладах «О состоянии окружающей природной среды Республики Татарстан» Министерства экологии и природной среды Республики Татарстан.</p> <p><bold>Результаты. </bold>В исследовании показана высокая степень связи между комплексным индексом загрязнения атмосферного воздуха канцерогенами и заболеваемостью населения раком легких (r=0,79 на уровне α=0,05). Также был проведен статистический анализ многолетнего уровня заболеваемости населения и ее связи с уровнем солнечной активности с использованием относительного числа солнечных пятен (число Вольфа – W). Коэффициент корреляции между W и заболеваемостью раком легких является значимым на уровне α=0,05 и составляет r=0,72, что свидетельствует о заметной силе связи между исследуемыми показателями.</p> <p><bold>Заключение.</bold> Совершенствование системы мониторинга, контроль за состоянием внешней среды, мероприятия по предотвращению загрязненности атмосферного воздуха способствуют снижению онкологической заболеваемости населения раком легких.</p></trans-abstract><kwd-group xml:lang="en"><kwd>lung cancer</kwd><kwd>geographic information system</kwd><kwd>air pollution with carcinogens</kwd><kwd>solar activity</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак легких</kwd><kwd>географическая информационная система</kwd><kwd>загрязнение атмосферного воздуха канцерогенами</kwd><kwd>солнечная активность</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Khripunova AA, Agapitova PD, Prikhodko RA, et al. 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